Stress-induced leukocytosis

Abstract:
In stress-induced leukocytosis, there is a redistribution phenomenon with no increased leukocyte production in the bone marrow. Various situations that can be termed stressful, like steroid therapy, epinephrine administration, cramps, fear and cigarette abuse, lead to a mobilization of the marginal pool (demargination). The neutrophils that adhere to venular endothelium are important here.

Clinical picture:
Apart from the induced stress phenomenon, no pathological state is present. The abnormality is quite frequent (smokers!) and should not be cause for further clinical evaluation. It usually disappears immediately in the absence of stress.

Hematology:
Leukocytosis is usually only minor and consists of a neutrophilia without shift to the left or toxic signs.

 


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