Pappenheimer bodies and siderocytes

Definition:
Pappenheimer bodies are fine-grained inclusions which are visible with Wright staining. Their iron content (hemosiderin) can be detected with iron staining. Erythrocytes with these types of inclusions are called siderocytes.

Occurrence:
Siderocytes are an indication of an iron utilization disorder. They occur with sideroblasic anemia, thalassemia and other severe anemias. 


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