Abstract:
The FAB-classification was developed in 1976 and is based on cytologic and cytochemical criteria for acute myeloid and lymphatic leukemias as well as myelodysplastic syndromes. FAB stands for French-American-British because it was group of French, US-American and British hematopathologists who developed this classification. The FAB-classification was replaced by the WHO-classification. Occasionally, it is still used for acute myeloid leukemias since it can be helpful in observing morphological aspects in the course of treatment.
| AML M0 | acute myeloblastic leukemia, minimally differentiated |
| AML M1 | acute myeloblastic leukemia, without maturation |
| AML M2 | acute myeloblastic leukemia, with granulocytic maturation |
| AML M2 baso | acute basophilic leukemia |
| AML M3 | acute promyelocytic leukemia |
| AML M3v | acute promyelocytic leukemia, microgranular variant |
| AML M4 | acute myelomonocytic leukemia |
| AML M4 eos | acute myelomonocytic leukemia together with bone marrow eosinophilia |
| AML M5a | acute monoblastic leukemia |
| AML M5b | acute monocytic leukemia |
| AML M6 | acute erythroid leukemias |
| AML M7 | acute megakaryoblastic leukemia |
| ALL L1 | acute lymphoblastic leukemia with small cells |
| ALL L2 | acute lymphoblastic leukemia with medium sized cells |
| ALL L3 | acute lymphoblastic leukemia with large cells |
| RA | refractory anemia |
| RARS | refractory anemia with ringed sideroblasts |
| RAEB | refractory anemia with excess of blasts |
| CMML | chronic myelomonocytic leukemia |
| RAEB-T | refractory anemia with excess of blasts in transformation |